IMC Forum. Content. Context. Connection. Register to learn more about cell segmentation.

Considerations for High-Plex Imaging Data Analysis

Session II: Tools and Trailblazers: Data Analysis Strategies and User-Developed Software Approaches

December 8, 2022

  • Experience a new, streamlined sample-to-analysis workflow solution for high-plex data.
  • Hear about the latest updates from the developer of histoCAT™.      
  • Learn from experts about high-plex analytical tools they developed.
  • Hear the experts talk about software tools and analytical approaches to get a deeper understanding of options for high-plex data analysis.

Submit the form to watch on-demand

Watch previous IMC Forums on-demand

Submit the form below to watch the videos.

Get familiar with performing data visualization, data preparation, single-cell segmentation and single-cell analysis.

Learn about commonly used open source and commercial software algorithms and analytical tools and how our experienced FAS team can help you decide on an approach to meet your research goals.

Hear how analysis from a multi-omics approach including RNA sequencing and Imaging Mass Cytometry (IMC) data was integrated to achieve key hepatocellular carcinoma insights.

Watch on demand

 

Speakers:


Wendell Smith

 

Wendell Smith, PhD
Senior Field Applications Scientist,
Standard BioTools

     

Won Jin Ho

 

Won Jin Ho, MD
Assistant Professor
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

     

Exploration of the tumor microenvironment (TME) is key to understanding the spatial relationships between cells and cell function in cancer pathology.

This IMC Forum started with a conversation about the impact of adding Imaging Mass Cytometry to the Lombardi Comprehensive Cancer Center at Georgetown University, which was followed by two presentations on research projects in hepatocellular carcinoma and colon cancer. 

In the panel discussion, three expert researchers shared their experiences and insights, then took questions so attendees could learn more about the potential advantages of IMC powered by CyTOF® technology for their research.

Watch on demand    

 

Related resources:

Immuno-oncology e-book: See two articles selected from the Drug Target Review highlighting findings that researchers believe could be used to enhance immunotherapies. This is supplemented with a short Expert View article by Standard BioTools Chief Science Officer Andrew Quong, PhD.

View now


IMC Trending Topics in Immuno-oncology article: Read about the latest research and past publications using IMC to explore the tumor-immune landscape, biomarker discovery and methods associated with therapeutics development.

­­­­View now

 

IMC Forum Agenda (All times shown in PT)

Welcome and Introduction
→ 7:30–7:35


Clinton Hupple

 
Clinton Hupple, MSc
Product Manager
Standard BioTools
     

One-on-One Conversation on the Impact of Imaging Mass Cytometry Capabilities at a Cancer Center
→ 7:35–8:00


Stephen Byers

 
Stephen Byers, PhD
Professor of Oncology and Associate Director
Georgetown Lombardi Comprehensive Cancer Center

Andrew Quong

 
Andrew Quong, PhD
Chief Science Officer
Standard BioTools
     

Understanding the Immune Microenvironment of Hepatocellular Carcinoma Using Imaging Mass Cytometry
→ 8:00–8:25


Won Jin Ho

 
Won Jin Ho, MD
Assistant Professor
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
     

Deciphering the Complexity of Anti-Cancer Immune Responses With Imaging Mass Cytometry
→ 8:25–8:50


Marieke Ijsselsteijn

 
Marieke Ijsselsteijn, PhD Candidate
Leiden University Medical Center
     

Panel Discussion
→ 8:50–9:25


Michelle Macpherson

 
Moderator: Michelle Macpherson, MSc
Director, Product Management, Imaging Mass Cytometry
Standard BioTools

Panelists:

  • Stephen Byers, PhD
  • Won Jin Ho, MD
  • Marieke Ijsselsteijn, PhD Candidate
     

Session Close
→ 9:25


Clinton Hupple

 
Clinton Hupple, MSc
Product Manager
Standard BioTools
     

IMC cell segmentation ESCH Epimods

After an introduction by Standard BioTools Chief Science Officer Andrew Quong, the event will include a presentation by Amy Bradshaw, PhD, Professor in the Division of Cardiology at the Medical University of South Carolina, and two panel discussions moderated by Hartland Jackson, PhD, Investigator at the Lunenfeld-Tanenbaum Research Institute.

The first panel discussion will feature hands-on experts addressing the current use of pipelines and offering up their tips, and the second will bring together three key thought leaders and expert algorithm developers to share their thoughts on the future of cell segmentation.

Watch on demand    

 

Related resources:

→ Watch presentations and discussions from the October 2021 IMC Summit: Uncovering Spatial Biology on demand.

View now


→ ImaBiotech, a CRO that offers IMC services, shares its years of experience with cell segmentation in this webinar.

­­­­View now

 

Agenda (All times shown in PT)

Introduction and presentation
 7:30–7:45

How Standard BioTools Can Help Prepare for Success in Cell Segmentation


Andrew Quong, PhD   
Andrew Quong, PhD
Chief Science Officer, Standard BioTools
     

Presentation (20 min) and Q&A (5 min)
 7:45–8:10

Mouse cardiac model – Identifying Macrophage Subsets in Murine Myocardium


Amy Bradshaw, PhD   
Amy Bradshaw, PhD
Professor, Division of Cardiology, Medical University of South Carolina
     

Panel discussions:
The Current Practice of Cell Segmentation

 8:10–8:35


Hartland Jackson, PhD   
Moderated by Hartland Jackson, PhD
Investigator, Lunenfeld-Tanenbaum Research Institute
 
Amy Bradshaw, PhD 
 
Amy Bradshaw, PhD
Professor, Division of Cardiology, Medical University of South Carolina
 
Nils Eling, PhD, MSCA 
 
Nils Eling, PhD, MSCA
Postdoctoral fellow, University of Zurich
 
Anthony Colombo, PhD 
 
Anthony Colombo, PhD
Graduate student in Biostatistics at the University of Southern California, in collaboration with Cedars-Sinai Graduate School
 
Fabian Schneider, PhD 
 
Fabian Schneider, PhD
Research Product Manager, Visiopharm
     

Panel discussions:
The Future of Cell Segmentation

 8:35–9:00


Hartland Jackson, PhD   
Moderated by Hartland Jackson, PhD
Investigator, Lunenfeld-Tanenbaum Research Institute
 
Beth Cimini, PhD 
 
Beth Cimini, PhD
Senior Group Leader, Broad Institute of MIT and Harvard
 
David Van Valen, PhD 
 
David Van Valen, PhD
Investigator, Department of Biology, Heritage Medical Research Institute, California Institute of Technology
 
Carsen Stringer, PhD 
 
Carsen Stringer, PhD
HHMI Janelia Research Campus
     

Unless explicitly and expressly stated otherwise, all products are provided for Research Use Only, not for use in diagnostic procedures. Find more information here.