Resources Blog

Unlocking deeper cellular insights at SITC 2023

Stay tuned for updates on our exciting new spatial proteomics solutions



Standard BioTools™ was in San Diego from November 1–5 for the Society for Immunotherapy of Cancer’s 38th Annual Meeting, which consisted of cutting-edge research presentations by experts, oral and poster abstract presentations and updates on major national and international initiatives from academia, government and industry. We were thrilled to meet so many attendees over our jam-packed time at the meeting and appreciated all of the interest shown in our cutting-edge technology and innovations!

Our booth was a highlight, with a delicious-smelling popcorn stand, fun swag like custom LEGO® sets and candy and a busy in-booth demo room. Visitors got an exclusive preview of new spatial biology solutions, including:

  • Flexible imaging modes
  • Automation to process hundreds of slides
  • RNA and protein co-detection on the same sample
  • End-to-end solutions to expedite the imaging workflow

Booth visitors also learned about how the key to robust immunotherapies starts with CyTOF® technology: CyTOF flow cytometry enables deep immune profiling without the challenges of complicated spectral overlap, resulting in precise and reproducible data, while Imaging Mass Cytometry™ (IMC™) allows one-step detection of 40-plus markers on the same sample without the challenge of autofluorescence.

Finally, we were excited to present six posters on a wide range of topics:

  • Poster #119 used the Maxpar OnDemand™ Mouse Immuno-Oncology IMC™ Panel Kit for multiparametric evaluation of the mouse tumor microenvironment (TME), presenting a consolidated single-cell analysis pipeline by combining the panel kit with the Maxpar® IMC Cell Segmentation Kit.
  • Poster #126 presented a deep phenotypic spatial analysis of various mouse and human brain tumors and identified cellular composition and activation of immuno-oncological processes within the TME.
  • Poster #912 used a 37-marker CyTOF immune profiling antibody panel to assess the effect of different commercially available blood preservation reagents and their impact on data quality.
  • Poster #914 presented a simplified flow cytometry workflow using CyTOF technology and preconfigured reagents to enable highly multiparametric phenotypic and functional characterization at the single-cell level.
  • Poster #958 combined the 30-marker Maxpar® Direct™ Immune Profiling Assay™ with add-on Expansion Panels to create a 42-marker panel to characterize multiple myeloma PBMC, allowing for deep immune profiling of T cells and NK cells in particular.
  • Poster #1490 presented a robust and reliable workflow combining RNAscope™ technology with the multiplexing capability of Imaging Mass Cytometry™ to visualize key RNA and protein markers in the same samples.

Thank you to everyone who took the time to visit our booth, attend an in-person or virtual demo and swing by our poster presentations. We loved hearing about how our tools and technology are a step above in helping researchers shed light on the immune system response to cancer and potential immunotherapy treatments.

LEARN MORE ABOUT OUR PRESENCE AT SITC


Check out other blog posts

Harness the power of mouse tumor models

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Bringing the CyTOF advantage to CAR cell therapy research

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The significance of the messenger

How we can tackle the complexity of cell signaling and translate this knowledge to what matters

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Unless explicitly and expressly stated otherwise, all products are provided for Research Use Only, not for use in diagnostic procedures. Find more information here.